Basavaraj Binjawadagi, M.S.
Food Animal Health Research Program
College of Veterinary Medicine
Primary Food Innovation Center Area: Food Security
Areas of Expertise: mucosal vaccine, PRRSV, mucosal adjuvant, PLGA delivery system, immune correlates of protection
We work on an economically important pig disease called porcine reproductive and respiratory syndrome (PRRS), caused by PRRS virus, a RNA virus. PRRS is annually causing nearly a $700 million loss to US swine industry alone. Presently used vaccines have failed to control the spread of the disease. Therefore, we are focusing on developing an effective adjuvanted mucosal vaccine for this disease. A novel delivery system (PLGA) for this candidate mucosal vaccine has shown significant promise in eliciting protective immune responses in vaccinated pigs when challenged with heterologous strains of PRRSV.