Zhongyan Lu, B.S.
Graduate Research Asociate
Veterinary Preventive Medicine
College of Veterinary Medicine
Primary Food Innovation Center Area: Food Safety
Areas of Expertise: Porcine sapovirus, gnotobiotic pig model, gastroenteritis, enteric immunology
Enteric caliciviruses are a major cause of non-bacterial gastroenteritis in humans. The enteric caliciviruses include noroviruses and sapoviruses. Sapoviruses are an emerging pathogen that can cause symptomatic and non-symptomatic gastroenteritis in the host. Sapoviruses are transmitted mainly in fecal-oral route. The research on human enteric caliciviruses is hampered for the lack of cell culture system. Porcine sapovirus Cowden strain has been adapted to cell culture. Therefore, it is a good surrogate for the research on sapovirus. The research on porcine sapoviruses is important to understand the nature of human caliciviruses and can help development of antivirals and vaccines.